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Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl} -4-)dimethylamino)-2-butenamide and crystalline forms thereof
专利权人:
Wyeth LLC
发明人:
Qinghong, Lu,Ku, Mannching Sherry,Chew, Warren,Cheal, Gloria K.,Hadfield, Anthony F.,Mirmehrabi, Mahmoud
申请号:
AU2016225895
公开号:
AU2016225895A1
申请日:
2016.09.09
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016225895A120160929.pdf#####ABSTRACT MALEATE SALTS OF (E)-N-{4-[3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO]-3CYANO-7-ETHOXY-6-QUINOLINYL}-4-(DIMETHYLAMINO)-2-BUTENAMIDE AND CRYSTALLINE FORMS THEREOF The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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