#$%^&*AU2020203496A120200618.pdf#####LAUR 4512WO ABSTRACT Bolaamphiphilic compounds are provided according to formula I: HG2 - HG1 where HG, HG2 and L' are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain. - 156-