Institute of Microbiology; Chinese Academy of Sciences
发明人:
Min Fang,Wei Jiang,Xiuling Gu,Dongfang Wang,Kaili Li
申请号：
US15745031
公开号：
US20180201689A1
申请日:
2016.06.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides an antibody fusion protein, comprising an antitumor antigen-specific antibody or a Fab fragment thereof, a single domain antibody or single chain antibody, and further comprising a human NKG2D ligand or ligand fragment. The human NKG2D ligand or ligand fragment and the antitumor antigen-specific antibody or Fab fragment thereof and the single domain antibody or single chain antibody are mutually connected by a linker peptide.
