Arrangements of components for use in support of a Hyperthermic Intraperitoneal Chemotherapy (HIPEC) System which conveys fluids from a system to a patient and back to the system in a complete circuit. The described arrangements provide multiple means of rapidly configuring the number of input lines and output lines into and out of the patient. Included are integral temperature probes in the inflow and outflow lines. Also included are various means of introducing and removing the fluids from the patient and additional temperature probes to be used at the discretion of the clinician.