Hannah Fiji;Michael J. Kelly, III;Kevin F. Gilbert;Swati I P. Mercer;Zhijian Zhao;Scott Wolkenberg;Pablo de Leon;Joseph E. Pero;Michael A. Rossi;Anthony J. Roecker;Lianyu;James Mulhearn;Mark E. Layton
发明人:
Mark E. Layton,Joseph E. Pero,Hannah Fiji,Michael J. Kelly, III,Pablo de Leon,Michael A. Rossi,Kevin F. Gilbert,Anthony J. Roecker,Zhijian Zhao,Swati I P. Mercer,Scott Wolkenberg,James Mulhearn,Lianyu
申请号：
US14353488
公开号：
US09273040B2
申请日:
2012.10.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed are compounds of Formula (A) or a salt thereof, wherein “Het”, Ra, and Rb are defined herein, which have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (A) or their salts, and methods of treating neuropathic pain disorders using the same.
