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use of a marker, methods for identifying a mammalian neural stem cell and / or a mammalian neural progenitor cell, for isolating a mammalian neural stem cell and / or a mammalian neural progenitor cell, to determine whether a compound of The test modulates a mammalian neural stem cell and / or mammalian neural progenitor cell differentiation in vitro, to produce an isolated mammalian cell population in vitro, to treat disease or damage and / or to prevent and protect against system damage. nervous system in an individual, to treat a mental or behavioral disorder in an individual and to determi
专利权人:
XINTELA AB
发明人:
EVY LUNDGREN ÅKERLUND,KATARZYNA CHMIELARSKA MASOUMI
申请号:
BR112019003147
公开号:
BR112019003147A2
申请日:
2017.08.17
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The present application relates to methods for detecting and isolating a population of neural stem cells (ctn) or neural progenitor cells (cpn) based on expression of the alpha10beta1 integrin marker; and also the use of said ctn or cpn population for therapy, diagnosis and prognosis of snc disease or damage.o presente pedido refere-se aos métodos para a detecção e o isolamento de uma população de células-tronco neurais (ctn) ou de células progenitoras neurais (cpn) com base na expressão do marcador integrina alfa10beta1; e, também, ao uso da dita população de ctn ou de cpn para terapia, diagnose e prognose de doença ou de dano do snc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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