PROCÉDÉ DE SUPPRESSION DE TUMEURS PAR INHIBITION DE LA FAMILLE MIR-200

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专利权人:

National University Corporation Chiba University

发明人:

申请号：

EP16851483.4

公开号：

EP3357498A4

申请日:

2016.09.27

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Tumor growth was found to be significantly suppressed in vivo by inhibiting both miRNA containing 5'-AACACUG-3' as a seed sequence and miRNA containing 5'-AAUACUG-3' as a seed sequence. The inhibition significantly altered the proportion of subpopulations of tumor cells and reduced the tumorigenicity in all subpopulations. The inhibition also exerted a remarkable tumor-shrinking effect on already-formed tumors. The present invention provides novel therapeutic potential against tumor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/