Elazar Rabbani,Xiaofeng Li,Dakai Liu,Yazhou Zhang,Richard Jin,Riddhi Bhattacharyya,Wei Cheng,James J. Donegan
申请号：
US16435981
公开号：
US20190350936A1
申请日:
2019.06.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands.
