RABBANI, ELAZAR,LI, XIAOFENG,LIU, DAKAI,ZHANG, YAZHOU,JIN, RICHARD,BHATTACHARYYA, RIDDHI,CHENG, WEI,ZHANG, GUANGRONG,LIANG, YUANXING,ENEA, VINCENZO,DONEGAN, JAMES J.
申请号:
CA2732013
公开号:
CA2732013C
申请日:
2009.08.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to the field of therapeutic methods,compositions and uses thereof, that affect, directlyor indirectly, the behavior of LRP receptors. These compositions and methodsresult in the treatment of inflammatory, immunologicaland metabolic conditions. More particularly, the methods and compositions ofthe invention are directed to the identificationof small molecules, drugs and/or pharmacological agents that affect the Wntpathway by affecting normal complex formationamong various signaling receptors, the LRP5 and LRP6 receptor, and relatedligands.