CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE

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专利权人:

发明人:

GAUZY, LAURENCE,ZHAO, ROBERT,DENG, YONGHONG,LI, WEI,BOUCHARD, HERVE,CHARI, RAVI, V.J.,COMMERCON ALAIN

申请号：

MYPI 20082798

公开号：

MY157715A

申请日:

2007.01.22

申请国别(地区):

MY

年份:

2016

代理人:

摘要：

THE PRESENT INVENTION RELATES TO NOVEL CYTOTOXIC AGENTS AND THEIR THERAPEUTIC USE. MORE SPECIFICALLY, THE INVENTION RELATES TO NOVEL CYTOTOXIC AGENTS COMPRISING TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE. THESE NOVEL CYTOTOXIC AGENTS HAVE THERAPEUTIC USE AS A RESULT OF DELIVERING THE TOMAYMYCIN DERIVATIVES TO A SPECIFIC CELL POPULATION IN A TARGETED FASHION BY CHEMICALLY LINKING THE TOMAYMYCIN DERIVATIVE TO A CELL BINDING AGENT. THE TOMAYMYCIN DERIVATIVES USEFUL IN THE PRESENT INVENTION HAVE THE FORMULA (I) SHOWN BELOW:

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中国工程科技知识中心

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http://www.ckcest.cn/home/