A sensor array, method of making same, and related medication compliance monitoring techniques are disclosed. In some embodiments, the array may include a plurality of electrically conductive traces including first and second electrically conductive traces that are electrically isolated from one another. The array also may include an electrically resistive element coupled with the first and second electrically conductive traces. The array may be configured to interface with a medication dispenser such that: the electrically resistive element is disposed over at least one medication compartment of the medication dispenser; and in expelling contents of the at least one medication compartment of the medication dispenser, the electrically resistive element is broken. In some embodiments, the array may be configured for use, for example, in monitoring medication compliance.