Henry Ford Health System;The Regents of the University of California
发明人:
Phillip Crews,Frederick A. Valeriote,Sheng Lin,Erin P. McCauley,Nicholas Lorig-Roach,Karen Tenney
申请号：
US16493690
公开号：
US20200129631A1
申请日:
2018.03.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided are pyrroloquinolin compounds of formula (1) or (II). In certain aspects, the pyrroloquinolin compounds are therapeutic, e.g., for treating a cell proliferative disorder. Also provided are conjugates that include the pyrroloquinolin compounds of the present disclosure. Compositions, e.g., pharmaceutical compositions, that include the pyrroloquinolin compounds and conjugates of the present disclosure are also provided. Further provided are therapeutic methods involving the administration of the pyrroloquinolin compounds, conjugates or compositions of the present disclosure. Kits that include the pyrroloquinolin compounds, conjugates or compositions are also provided.
