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Process for the preparation of pleuromutilins
专利权人:
NABRIVA THERAPEUTICS GMBH
发明人:
ROSEMARIE, RIEDL,WERNER, HEILMAYER,LEE, SPENCE
申请号:
TR201802636
公开号:
TR201802636T4
申请日:
2011.05.23
申请国别(地区):
TR
年份:
2018
代理人:
摘要:
A process for the preparation of a compound of formulain the form of a single stereoisomer, comprising deprotecting the amine group in an N-protected amino-hydroxy-cyclohexylsulfanyl-acetyl-mutilin of formulawherein R is an amine protecting group in the form of a single stereoisomer,and isolating a compound of formula I in the form of a single stereoisomer obtained from the reaction mixture; compounds obtainable by such processes, e.g. a compound of formula I in a crystalline form, or salts of a compound of formula I in crystalline form, and processes for the preparation of intermediates for the production of a compound of formula I.Mevcut buluş, kristalin 14-O-{[(4-amino-2-hidroksi-sikloheksil)-sulfanil]-asetil}-mutilin, bunun hazırlanması için yeni prosesler ve bunun kristalin tuzları ile ilgilidir.
来源网站:
中国工程科技知识中心
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