Novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and pharmaceutical composition containing same
Choi, Soongyu,Choi, Jungsub,Yoon, So-Hyun,Kim, Yoo Hoon,Kim, Jae Yeon,Lee, Suk Ho,Cho, Young Lag,Song, Ho Young,Lee, Dae Yon,Baek, Sung Yoon,Chae, Sang Eun,Park, Tae Kyo,Woo, Sung Ho,Kim, Yong Zu
申请号:
AU2014400894
公开号:
AU2014400894A1
申请日:
2014.07.18
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.