Crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and pharmaceutical composition comprising same
Soongyu Choi,Jungsub Choi,So-Hyun Yoon,Yoo Hoon Kim,Jae Yeon Kim,Suk Ho Lee,Young Lag Cho,Ho Young Song,Dae Yon Lee,Sung Yoon Baek,Sang Eun Chae,Tae Kyo Park,Sung Ho Woo,Yong Zu Kim
申请号：
US15325521
公开号：
US09988372B2
申请日:
2014.07.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.
