Акционерное общество "Зеленоградский нанотехнологический центр" (RU)
发明人:
Морозов Роман Андреевич (RU),Ромашкин Алексей Валентинович (RU),Левин Денис Дмитриевич (RU)
申请号：
RU2015112383
公开号：
RU2015112383A
申请日:
2015.04.07
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A biodegradable material on the basis of molecules of proteins and biopolymer fibers, which can act as collagen, chitosan or other natural biopolymers or their modification in the form of fibers, wherein the fibers biopolymers derived molecules with a molecular weight of from 70 kDa to 1000 kDa, deatsetelirovaniya with a degree of from 50 to 100% not tested artificial chemical modifications and interact with proteins in the molecule as a binder to form a uniform nano Cleto -screw frame containing fiber diameter of 20 to 500 nm, which provides simultaneous combination of the following properties: bioresorbability, liquid sorption of at least 100% by weight of dry material, acceleration proliferative activity in cell cultivation, as well as the acceleration of tissue regeneration during surgery of internal organs, mechanical tensile strength of not worse than 1 MPa.2. A biodegradable material according to Claim. 1, wherein the protein in the form for example of animal or vegetable origin albumin or any other protein bioresorbable or water-soluble organic polymer / -oligomera or a mixture of several different organic polymers / -oligomerov or their derivatives capable of reacting between themselves and chitosan fibers, encapsulate and / or link the chitosan fibers and / or collagen, including treating the solution with a temperature in the temperature range, on the one hand ensuring early lo process denaturing of protein molecules on the other - the preservation properties of the fibers of at least one of the biopolymers employed, including the presence of collagen fibers,1. Биодеградируемый материал на основе молекул белков и волокон биополимеров, в качестве которых могут выступать коллаген, хитозан или иные биополимеры или их природные модификации в виде волокон, отличающийся тем, что волокна биополимеров, образованные молекулами с молекулярной массой от 70 кДа до 1000 кДа, со степенью деацетелирования от 50 до 100%, не проходят химической искусственной модификаци
