USE OF A COMBINATION OF AN INHIBITOR OF THE IF CURRENT OF THE SINUS NODE AND AN INHIBITOR OF THE ANGIOTENSIN CONVERTING ENZYME FOR THE TREATMENT OF HEART FAILURE
ROUSSEL JEROME,FELDMANN LUC,LEREBOURS-PIGEONNIERE GUY
申请号：
AP2016009002
公开号：
AP2016009002A0
申请日:
2011.06.14
申请国别(地区):
AP
年份:
2016
代理人:
摘要：
Combination (I) comprises a selective and specific sinusal I f(mixed sodium ion-potassium ion inward current) current inhibitor (A) and an angiotensin converting enzyme inhibitor (B). An independent claim is included for pharmaceutical compositions comprising: ivabradine, in the form of hydrochloride or its hydrate or crystalline forms, and perindopril, in the form of salt of tert-butylamine or arginine or their hydrates or crystalline forms, alone or in combination with one or more excipient. ACTIVITY : Cardiant； Cardiovascular-Gen.； Vasotropic； Antianginal； Antiarrhythmic. MECHANISM OF ACTION : Sinusal I fcurrent inhibitor； Angiotensin converting enzyme inhibitor.
