Combinations of protease inhibitors such as VX-950 and polymerase inhibitors for the treatment of HCV infection

• 收藏
• 分享

专利权人:

INC.;VERTEX PHARMACEUTICALS

发明人:

KWONG, ANN,MANI, NAGRAJ,ZHOU, YI,LIN, CHAO

申请号：

NZ58091709

公开号：

NZ580917A

申请日:

2008.05.05

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a therapeutic combination comprising a protease inhibitor VX-950 that is effective to inhibit the function of HCV NS3 protease in a mammal and a nucleoside polymerase inhibitor selected from the group consisting of NM107, R7128 and IDX184 that inhibit the activity of HCV RNA dependent RNA polymerase (RdRp). The disclosure also relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV infection or alleviating one or more symptoms thereof in a patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/