Cathy Ann-Rasmussen Ivarie;B. Lynn Allen-Hoffmann;Christina L. Thomas-Virnig
发明人:
B. Lynn Allen-Hoffmann,Cathy Ann-Rasmussen Ivarie,Christina L. Thomas-Virnig
申请号:
US11365357
公开号:
US09163076B2
申请日:
2006.03.01
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates generally to compositions for wound healing. More specifically, the present invention provides human skin equivalents engineered to express exogenous proteinase inhibitor polypeptides (e.g., TIMP-1 polypeptides) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.