One-piece heart prosthesis implantable in an anatomical position. Accordingto the invention, the artificial left and right ventricles (2, 8) have generaldirections (14, 15) arranged in an asymmetrical V shape, such that said ventriclesapproach each other as they move away from the means (6, 12) of connection to thenatural left and right auricles, and the individual hydraulic actuators (7,13), associated respectively with said artificial left and right ventricles(2, 8), are arranged near each other, in proximity to said artificial left ventricle(2).