Pharmaceutical compositions comprising the combination of a non-steroidal antiinflammatory agent and a xanthine oxidase inhibiting agent useful for the control and treatment of gout, gouty arthritis and related diseases.
VICTOR GUILLERMO ÁLVAREZ OCHOA,MARIA ELENA GARCIA ARMENTA,JOSEFINA SANTOS MURILLO
申请号:
BRPI0817563
公开号:
BRPI0817563A2
申请日:
2008.09.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention relates to a pharmaceutical composition comprising the synergic combination of a nonsteroidal anti-inflammatory agent known as meloxicam or celecoxib and a xanthine oxidase inhibiting agent know as allopurinol, as well as pharmaceutically acceptable excipients, which are formulated in a single dosage unit to be administered orally. The compositions, which are used to control and treat gouty disease or gout, gouty arthritis and other related diseases, provide an improved therapeutic effect and faster pharmacological action in less time, reducing pain, inflammation and plasma urate levels, as well as providing reductions in the doses administered, the risk of severe complications and the risk of side effects.