II;Alton Samuel Kelley, II;James Gregory Sullivan;Alton Samuel Kelley
发明人:
Alton Samuel Kelley, II,James Gregory Sullivan
申请号：
US12571990
公开号：
US08410092B2
申请日:
2009.10.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to a pharmaceutical composition that includes a combination of about 2-5 milligrams of a non-steroidal anti-inflammatory drug and from about 2-30 milligrams of an opioid analgesic in a single pharmaceutical dosage unit that can provide effective chronic pain management with the added benefit of reduced side effects such as withdrawal and gastrointestinal disorders. The non-steroidal anti-inflammatory drug may be piroxicam and the opioid analgesic may be buprenorphine. The present invention also provides for a method of managing pain in a patient that includes administering the pharmaceutical composition previously described. The pharmaceutical composition previously described may be administered in a single or multiple dosage regimen.
