<；P>；PROBLEM TO BE SOLVED: To provide a type IV collagen production promoter having an excellent action and high safety, a transglutaminase-1 production promoter, a serine palmitoyltransferase (SPT) production promoter, an aquaporin 3 (AQP3) production promoter, an involucrin production promoter, an HMG-CoA reductase (HMGCR) production promoter and an adenosine triphosphate (ATP) production promoter. <；P>；SOLUTION: The type IV collagen production promoter, the transglutaminase-1 production promoter, the serine palmitoyltransferase (SPT) production promoter, the aquaporin 3 (AQP3) production promoter, the involucrin production promoter, the HMG-CoA reductase (HMGCR) production promoter and the adenosine triphosphate (ATP) production promoter include each a royal jelly extract as an active ingredient. <；P>；COPYRIGHT: (C)2009,JPO&INPIT
