A. compound, the meaning of formula (1) is that x is O, NH, ch832222 or link; R 1 is c8332183318326;R2,R2',R3,R3',R830808,R830808',R83099,R830909's, independent of each other, h, Cl, Br, I, oh, - (ch832222) - Oh, cf832323;No.8322;8323,CN,S(o)8346;-R8310;O-S (O)..1. Lease c833218331832626-s (o) 8346; - r8310;1. Lease c833218331832626-o-s (o) 8346; - r8310;Cooh,Coo-Ochielo C83218331383262,Conh83222,Conh-Acquilo C8321E.8331832626,A. including [c8332121] 83318326;1. Lease land No. c833218331 and 832626;Alquenilo C83228331-832626;1. C 83228331 asphalt;O-asphalt c83218c31832626;1. In the matrix, more than one or all water bodies can be replaced by fluorine; phenyl, - (ch8322) - phenyl, - (ch8322) - phenyl, - (ch8322) - 8345; - phenyl, O - (ch83244); - phenyl, - (ch8322) - O - (ch832244); - phenyl, in which the phenyl ring can be replaced by F, Cl, Br, I, oh, 238383 by one to three times;No.8322;CN,OCF8323,O-asphalt c83218c31832626;1. Lease land No. c833218331 and 832626;NH.8322;NH-Acquilo C83217C8331832626,N (lease No. c8332121) 833183226;-C832223;Cooh,Coo-Ochielo C83218331383262,Conh832222;There's at least one activist there,R2',R3,R3',R830808,R830808',R83099,R83099a ` has the meaning of − o - (ch832222) - 8344; - phenyl o - (ch8322) - or - (ch8324) - phenyl, wherein the phenyl ring can be replaced by F, Cl, Br, I, oh, cf832323 by 1 to 3 times;No.8322;CN,OCF8323,O-asphalt c83218c31832626;1. Lease land No. c833218331 and 832626;NH.8322;NH-Acquilo C83217C8331832626,N (lease No. c8332121) 833183226;-C832223;Cooh,Coo-Ochielo C83218331383262,Conh832222;R8310es h, oh, rental seat c833218331832626;NH.8322;NH-Acquilo C83217C8331832626,N (lease No. c8332121) 833183226;N is 2, 3, 4, 5, 6; m is 1, 2, 3, 4, 5, 6; P is 0, 1, 2; and the salts that can be accepted in medicine, the preparation method, including the medicine and use of these compounds. Requirement 12: a compound (2) having formula properties,(3) or (4),There are also acceptable effectsUn compuesto que tiene la fórmula (1