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It is composed of pyridine-3-carboxamida and its pharmacology
专利权人:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
YOUNGMAN, MARK ANDREW,SHEARER, BARRY GEORGE,DEATON, DAVID NORMAN
申请号:
ARP180101571
公开号:
AR112084A1
申请日:
2018.06.11
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
A pyridine-3-carboxamida compound with (1) equation,X is n, y is C, X is he, y is n, or X is n, y is n; R1 is not or selected from hydrogen, fluorine, chlorine, bromine, iodine, cyanogen-or83099;1. Lease No. c8332183318325j;Replaced lease No. c83321313525, cycloquilo c83233318325;1. Cycloquilo c8331832325 and isocycloaryl; R2 was selected from hydrogen, fluorine, chlorine, bromine, iodine, cyanogen-or83099;-SR8310;1. Lease No. c8332183318325j;Replaced lease No. c83321313525, cycloquilo c83233318325;e. Cycloquilo c832232383318325 (replace 1 to 4 substitutes independently selected from fluorescence, chlorine, bromine, iodine, tar c8332183318324oxy Oh tar c8332183331c832424);Oxo,cooh,no832222,-NH 8322Y-CN,Amino,NHR8311;-8311; 831222;a. Azetidini and azetidini (replaced by 1 to 4 substitutes independently selected from fluorine, chlorine, bromine, iodine and tar c833218331838324);Oxo,cooh,no832222,-NH 8322Y-CN,a. Selected from c8332483318327a;An abiotic cyclopropyl compound consisting of 4, 5 or 6 members, consisting of one or two abiotic atoms selected independently from O and N; an abiotic compound consisting of 5 to 12 members, consisting of one or two abiotic atoms, at least one of which is nitrogen, the second abiotic atom, if any, is selected from n and S; R3 ° and r830808 are independently selected from the following substances: hydrogen; OS (o) 8322; nh8322;-S(O)8322CH8323,-Oh. - C º n, F, Cl, Br, I, tetrazolilo, metl tetrazolilo, ethi tetrazolilo, cycloquilo, cycloaquilo, cycloaquilo, cycloaquilo are replaced by one or two alternatives independently selected from them; fluoro, oh och, 23;Y-CH8323,Morphine, azidinia and azidinia were replaced by one or two substitutes independently selected from fluorination, chlorine, bromine and iodine-oh-cf832323;Y-CH8323,Pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroids, pyrethroidsOxazolilo is replaced by -
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