Tae Bo Sim,Young Jin Ham,Kyung Ho Yoo,Chang Hyun Oh,Jung Mi Hah,Hwan Kim,Hwan Geun Choi,Jung-Hun Lee
申请号:
US12858114
公开号:
US08329708B2
申请日:
2010.08.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are a 1,3,6-substituted indole compound having inhibitory activity for protein kinases, a pharmaceutically acceptable thereof, and a pharmaceutical composition for prevention and treatment of diseases caused by abnormal cell growth including the compound as an active ingredient.Since the novel indole compound exhibits superior inhibitory activity for various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating cancers caused by abnormal cell growth.