In one embodiment, a system for determining physiological parameters from blood flow dynamics includes a catheter configured for insertion into a blood vessel of a subject through which blood flows, a flexible barrier associated with the catheter configured to oscillate in response to changes in pressure of the blood within the catheter, and a pressure field microphone configured to measure a pressure field induced by the oscillation of the flexible barrier and to generate a measured acoustic pressure signal that can be processed to determine the physiological parameters.
