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Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery
专利权人:
Min Hyo Seo
发明人:
Min Hyo Seo,Sa-Won Lee,Myung-Han Hyun,Jeong-Il Yu,Dong-Hoon Chang,Hye-Jeong Yoon,Jeong-Kyung Kim
申请号:
US11974196
公开号:
US08349306B2
申请日:
2007.10.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.
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