Stein, Pascal Andre,Super, Michael,Davis, Jonathan H.
申请号:
AU2006332155
公开号:
AU2006332155B2
申请日:
2006.12.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Anti-CD19 B4 antibodies with modified variable regions are disclosed. The modified anti-CD19 variable region polypeptides have alterations to one or more framework regions or complementarity determining regions of the heavy chain variable region or light chain variable region, thereby to reduce a T-cell response.