GENKIN, DMITRY DMITRIEVICH,TETS, GEORGY VIKTOROVICH,TETS, VIKTOR VENIAMINOVICH
申请号:
CA3088723
公开号:
CA3088723A1
申请日:
2019.01.15
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention relates to the liver-specific delivery and/or expression of an enzyme which has a deoxyribonuclease (DNase) activity for enhanced clearance of cell free DNA (cfDNA) accumulated in hepatic porto-sinusoidal circulation and the use of such liver-specific delivery and/or expression for treatment of various diseases and conditions, including cancer and neurodegeneration.