The subject matter discloses a method and apparatus for detecting an environment within a body comprising a stylet and a catheter capable of being inserted into the body and a bio-sensing module for detecting a predefined material within the body, upon insertion of the stylet and catheter with close proximity to the predefined material. The predefined material may be beta-transferrin, and the apparatus may comprise a transmitter and an indication unit for transmitting data related to the presence of the predefined material in the body.