Method, system, and computer program product are provided for processing an ultrasound image, in particular an image of inhomogeneous tissue. The method includes: segmenting tissue in a received ultrasound image； creating a mask of pixels centred on a pixel in a tissue area, wherein the pixels in the mask are within a given decibel range of the central pixel and within a segmentation boundary； and assigning an attenuation to the central pixel by estimating the attenuation of the pixels in the mask. The received ultrasound image may be a raw image the method may include creating an image of an attenuation mapping of attenuations for each pixel in a tissue area. Alternatively, the received ultrasound image may be a time gain compensated image the method may include determining areas of relatively high or low attenuation.提供用於處理超音波影像，特定言之不均勻組織之影像的方法、系統及電腦程式產品。方法包括：在已接收超音波影像中對組織分段；產生以組織區域中像素為中心的像素之遮罩，其中遮罩中的像素處於中心像素之給定分貝範圍之內且處於分段邊界之內；以及藉由估計遮罩中的像素之衰減將衰減分配至中心像素。已接收超音波影像可為原始影像，方法可包括產生組織區域中之每個像素之衰減的衰減圖的影像。或者，已接收超音波影像可為時間增益補償影像，方法可包括決定相對高的或低的衰減之區域。
