Doris Stoermer,Joseph F. Dellaria, Jr.,David T. Amos,Bernhard M. Zimmermann,Luke T. Dressel,Jason D. Bonk,Matthew R. Radmer
申请号:
US12974459
公开号:
US08541438B2
申请日:
2010.12.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.