The United States of America;as represented by the Secretary;Department of Health and Human Services
发明人:
Alena Gros,Steven A. Rosenberg
申请号:
US15567157
公开号:
US20180148690A1
申请日:
2016.04.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer.