Novel tumor-specific T cell receptor

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专利权人:

マックス－デルブリュック－セントラム;メディツィン（エムディーシー）;ベルリン－ブッフ;モレクラーレ;フュア

发明人:

ブランケンシュタイン，トーマス,ヴィリムスキー，ゲラルト

申请号：

JP2015544487

公开号：

JP6615612B2

申请日:

2013.11.29

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

The present invention relates to a method for the production of novel T-cell receptors (TCR) which provide a reduced risk of adverse events in immune therapy, specifically in adoptive T cell transfer. The TCRs produced according to the method of the invention are specific for tumor cells and do not react with healthy tissue. Furthermore provided are nucleic acids encoding the TCR of the invention, vectors and host cells comprising the TCRs of the invention as well as their use is the treatment of tumorous diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/