ALLVIVO VASCULAR, INC.; INC.;THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY;ALLVIVO VASCULAR
发明人:
NEFF, JENNIFER A.,JOSHI, PRANAV R.,MCGUIRE, JOSEPH
申请号：
EP08781717
公开号：
EP2182798A4
申请日:
2008.07.11
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.
