A fogging device for disinfecting an enclosed area with an atomized disinfectant fluid may include a housing, and an atomizing disinfectant generator carried by the housing and including a disinfectant fluid reservoir, a compressor coupled to the disinfectant fluid reservoir, and an atomizing nozzle in fluid communication with the disinfectant fluid reservoir. A first processor may be carried by the housing and coupled to the compressor and configured to perform a treatment cycle during which the compressor is operated to dispense atomized disinfectant fluid from the disinfectant fluid reservoir into the enclosed area via the atomizing nozzle. The treatment cycle may include a saturation phase wherein the compressor operates to dispense atomized disinfectant fluid continuously to bring the enclosed area to a target saturation level, and a pulse phase wherein the compressor operates to intermittently dispense atomized disinfectant fluid to maintain the enclosed area at the target saturation level.
