The present invention discloses an integrated device for breast disease diagnosis and treatment, which includes a control host system, and a thermalgraphy subsystem, an ultrasoudimaging subsystem and a phonophoresis subsystem respectively in communication connection with the control host system. A display terminal is electrically connected to the control host system, and the control host system further has an intelligent interpretation expert system. The thermalgraphy subsystem is configured to perform infrared detection on breast to find an abnormal area the ultrasoudimaging subsystem is configured to display structural changes of the abnormal area the intelligent interpretation expert system is configured to perform a rational diagnosis and treatment scheme according to the detection results, in combination with a prestored image feature knowledge base of breast diseases and the phonophoresis subsystem is configured to perform target drug permeation therapy according to a prompt of the intelligent interpretation expert system.