A device (26) for the prevention of stroke is provided that has a processor (70), a compression system (49), a compression member (27), and a vascular probe (66)carried by the compression member. The vascular probe senses a parameter of a circulation system from a closed neck artery (12, 16) that is not being externally accessed. The processor processes the closed parameter and based upon this processing communicates with the compression system to instruct the compression system to actuate the compression member. The compression member and vascular probe are external to the interior of the patient when the vascular probe senses the closed parameter of the circulation system.