A system for ozone sterilization of waste material, includes a tank configured to receive waste material, ozonated water, and ozone gas. The system further includes a pump coupled to the tank to receive the waste material and the ozonated water from the tank and form a slurry. The pump includes a cutter assembly to reduce a particle size of the slurry through cutting. Additionally, the system includes a circulation loop coupled between the tank and the pump to receive the slurry from the pump and re-circulate the slurry to the tank until the slurry is sterilized. A method for ozone sterilization of waste material is also disclosed.