Zhang, Xujia,Gao, Xiang,Guan, Hongtao,Thøgersen, Henning,Sass-Ørum, Kristian,Iversen, Lars Fogh,Nørgaard, Per,Jørgensen, Sebastian Beck,Hansen, Kristian Tage,Wang, Yi
申请号:
AU2017269496
公开号:
AU2017269496A1
申请日:
2017.05.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
160031WO03 56 ABSTRACT The invention relates to MIC-1 compounds. More specifically it relates to compounds comprising a MIC-1 polypeptide and an N-terminal amino acid extension, wherein said extension consists of 3 to 36 amino acid residues and where the compound has a calculated pI lower than 6.5. The compounds of the invention have MIC-1 activity. 5 The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.