Xujia Zhang,Xiang Gao,Hongtao Guan,Henning Thoegersen,Kristian Sass-Oerum,Lars Fogh Iversen,Per Noergaard,Sebastian Beck Joergensen,Kristian Tage Hansen,Yi Wang
申请号：
US16303516
公开号：
US20190248852A1
申请日:
2017.05.24
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to MIC-1 compounds. More specifically it relates to compounds comprising a MIC-1 polypeptide and an N-terminal amino acid extension, wherein said extension consists of 3 to 36 amino acid residues and where the compound has a calculated pI lower than 6.5. The compounds of the invention have MIC-1 activity. 5 The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.
