COGNATE BIOSERVICES, INC.;NORTHWEST BIOTHERAPEUTICS, INC.;REVIMMUNE, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
BOSCH, MARNIX LEO,GANJEI, JAMES KELLY,POWERS, LINDA F.,LIAU, LINDA M.,PRINS, ROBERT M.
申请号:
CA2929407
公开号:
CA2929407A1
申请日:
2014.11.05
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure arises at least in part from the seminal recognition that a combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, or a medically beneficial response by a tumor.