COGNATE BIOSERVICES, INC.;NORTHWEST BIOTHERAPEUTICS;Revlmmune, Inc.;The Regents of the University of California
发明人:
Marnix Leo Bosch,James Kelly Ganjel,Linda F. Powers,Linda M. Liau,Robert M. Prins
申请号:
US14533879
公开号:
US20150273033A1
申请日:
2014.11.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure arises at least in part from the seminal recognition that a combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, or a medically beneficial response by a tumor.