Embodiments of the present invention provide a surgical cassette with compliant clamping zones to provide more uniform loading. According to one embodiment of the present invention, a surgical cassette includes a clamping portion that is configured to deform to conform to non-uniform load profile applied to the cassette. The clamping portion can include ribs that are sized and made of a suitable material such that the ribs will deflect predictably in the elastic region and flow plastically when the material yield point isexceeded. Theuse of ribs creates discrete small load areas that will deflect and distort predictably and non-catastrophically at high loads. This allows for the absorption of accumulated tolerances between the clamping mechanism and cassette (e.g., the non-parallelism between the clamping mechanism and cassette) while still providing a distributed load on the cassette.本發明的實施例提供一種外科手術卡匣具有順應性夾持區以提供更均勻的負載。依本發明之一實施例,一手術卡匣包含一夾持部係被構製成可變形來順應施加於該卡匣的不均勻負載輪廓。該夾持部可包含多數凸肋,其會被定寸並由一適當材料製成,而使該等凸肋會在彈性區中可預知地變形,且當超過該材料的屈服點時將會塑性地流變。該等凸肋的使用會造成個別的小負載區域,其將會可預知地偏轉和扭曲,並在高負載時非破壞性地變形。此乃可吸收該夾持機構與卡匣之間的累積公差(例如該夾持機構和卡匣之間的不平行),而仍可在該卡匣上提供一散佈的負載。