VAN DER VEER, ERIC PETER,VAN ZONNEVELD, ANTON JAN,PRINS, JURRIEN
申请号：
CA3092817
公开号：
CA3092817A1
申请日:
2019.03.01
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to antisense molecules and methods for modulating splicing of polyomavirus T antigen pre-mRNA. In one aspect the invention relates to an antisense oligonucleotide 12 to 30, preferably 17, 18, 19 or 20 to 30 nucleobases in length which comprises a sequence that is the reverse complement of a contiguous stretch of at least 12 nucleobases of a polyomavirus T-antigen pre- mRNA and which antisense oligonucleotide can modulate splicing of said T-antigen pre-mRNA in a cell.
