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COMPOUND HAVING SOMATOSTATIN RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE THEREOF
专利权人:
ONO PHARMACEUTICAL CO.; LTD.
发明人:
ISHIDA, Akiharu,YOSHIDA, Atsushi,MIYATA, Hidenori,SHONO, Tomoyuki
申请号:
SG11201907240X
公开号:
SG11201907240XA
申请日:
2018.02.07
申请国别(地区):
SG
年份:
2019
代理人:
摘要:
R HN (R 6 )n (I) 137 [] The present invention provides a somatostatin receptor subtype 2 agonist. The compound disclosed herein represented by the general formula (I): 5 wherein all symbols have the same meanings as the definitions described in the specification; or a salt thereof is a low-molecular compound having strong agonistic activity for somatostatin receptor subtype 2 and can 10 be orally administered. Therefore, the present compound can be easily administered and can alleviate pain accompanied by the therapy of patients. The present compound also has sufficiently weak hERG inhibitory activity and/or phospholipidosis action relative to the SSTR2 agonistic 15 activity, and thus can suppress or alleviate side effects resulting from the activity/action.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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