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Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof
专利权人:
Ltd.;Ono Pharmaceutical Co.
发明人:
Ishida, Akiharu,Yoshida, Atsushi,Miyata, Hidenori,Shono, Tomoyuki
申请号:
AU2018219644
公开号:
AU2018219644A1
申请日:
2018.02.07
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Provided is a somatostatin receptor subtype 2 agonist. A compound disclosed in the present invention that is represented by general formula (I) (wherein each symbol has the same meaning as defined in the description) or a salt thereof is a low molecular compound having a strong agonistic activity to somatostatin receptor subtype 2. The compound according to the present invention can be orally administered and, therefore, can be easily taken and contribute to the reduction of patient's pain associated with a therapeutic treatment. Moreover, the compound according to the present invention has sufficiently weak hERG inhibitory activity and/or phospholipidosis effect, compared with the SSTR2 agonistic activity thereof, and, therefore, can inhibit or suppress side effects caused by the aforesaid activity and/or effect.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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