A dry powder inhaler consisting of a reusable base unit and a disposable drug package is disclosed. The reusable portion may house a transducer, a controller, battery and user interface. The disposable portion may house a dose pellet in a sealed dose chamber that includes an integrated mouthpiece. A user may couple the disposable portion to the reusable portion of the inhaler. The inhaler may sense the user's breathe and synchronize delivery of the pharmaceutical or drug to the user.
