WUHAN NEUROPHTH BIOLOGICAL TECHNOLOGY LIMITED COMPANY
发明人:
Bin LI
申请号：
US16836644
公开号：
US20200263172A1
申请日:
2020.03.31
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed herein is a recombinant nucleic acid, comprising: a mitochondrial targeting sequence； a mitochondrial protein coding sequence, wherein said mitochondrial protein coding sequence encodes a polypeptide comprising a mitochondrial protein； and a 3′；UTR nucleic acid sequence. Also disclosed is a pharmaceutical composition comprising the recombinant nucleic acid and a method of treating Leber's hereditary optic neuropathy (LHON) using the pharmaceutical composition.
